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Year : 2020  |  Volume : 10  |  Issue : 1  |  Page : 81-82

Improved quality of life in patients with dentin hypersensitivity

Department of Conservative Dentistry and Endodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, India

Date of Submission20-May-2019
Date of Decision07-Jun-2019
Date of Acceptance25-Jun-2019
Date of Web Publication27-Dec-2019

Correspondence Address:
Dr. P Ajitha
Department of Conservative Dentistry and Endodontics, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, 162, Poonamallee High Road, Chennai - 600 077, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/sej.sej_81_19

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How to cite this article:
Janani K, Ajitha P, Sandhya R. Improved quality of life in patients with dentin hypersensitivity. Saudi Endod J 2020;10:81-2

How to cite this URL:
Janani K, Ajitha P, Sandhya R. Improved quality of life in patients with dentin hypersensitivity. Saudi Endod J [serial online] 2020 [cited 2022 Sep 25];10:81-2. Available from: https://www.saudiendodj.com/text.asp?2020/10/1/81/274196


Dentin hypersensitivity seems to be a common problem and still remains an enigma in diagnosis. The discomfort that arises as a result of dentin hypersensitivity is said to greatly affect the quality of life of the patients. On reviewing the literature, the prevalence of dentin hypersensitivity can range anywhere from 4.8% to 62.3%.[1] The success of treating dentine hypersensitivity mainly depends on the long-term efficiency of treatment modalities. The treatment modalities include the use of desensitizing chemical agents and LASER.[2]

To the best of our knowledge, till date, based on the evidence from clinical trial, the long-term prognosis of desensitizing toothpaste has not yet been clearly identified. Most of the clinical trial evaluated the prognosis only till the period of 12 weeks; hence, more trial is necessary. Moreover, some clinical trials were reported with publication bias. Many company-sponsored clinical trials reported the results which favor the benefit of the company, but the adverse outcome was not addressed.[3],[4] In the recent years, LASER seems to provide promising results. The mechanism of action differs with the type of LASER. Low-power LASER has a biomodulatory effect; cellular metabolic activity of odontoblast gets increased thereby blocking the dentinal tubules. Whereas, high-power LASER increases the surface temperature and promotes recrystallization of dentinal surface that results in blockade of dentinal tubules.[5] The previous report stated that adhesives like cyanoacrylate have higher efficiency than LASER.[6] Furthermore, regenerative procedures such as guided tissue regeneration with a three-layered membrane lead to successful results in the management of hypersensitivity. 8% nanocarbonated hydroxyapatite collagen/poly (lactic-co-glycolic acid) (nCHAC/PLGA) forms the inner porous membrane, 4% nCHAC/PLGA forms the middle layer, and PLGA forms nonporous outer membrane. When placed, it forms highly biocompatible membrane which helps in tissue regeneration.[7]

In the recent years, dynamic biological agents, namely stem cells such as stem cells from apical papilla, dental pulp stem cells (DPSC), and scaffold attribute to de novo regeneration of dentin. However, the challenge is that the functional regeneration of dentin depends on enamel regeneration. The availability of Dental Epithelial Stem Cells (DESC) that is responsible for enamel regeneration is very scarce.[8] Porcine epithelial rests of Malassez when cultured with DPSC can differentiate into enamel. The challenge in de novo enamel regeneration is time frame. It requires many years to form enamel which is not compatible with our clinical needs, and even if there is mild disturbance during the process, it may lead to defective enamel formation.

However, lot of research is still ongoing in achieving the ultimate goal in the treatment of dentin hypersensitivity which is the permanent relief of discomfort thereby improving the patients' quality of life.

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Favaro Zeola L, Soares PV, Cunha-Cruz J. Prevalence of dentin hypersensitivity: Systematic review and meta-analysis. J Dent 2019;81:1-6.  Back to cited text no. 1
da Rosa WL, Lund RG, Piva E, da Silva AF. The effectiveness of current dentin desensitizing agents used to treat dental hypersensitivity: A systematic review. Quintessence Int 2013;44:535-46.  Back to cited text no. 2
Lexchin J, Bero LA, Djulbegovic B, Clark O. Pharmaceutical industry sponsorship and research outcome and quality: Systematic review. BMJ 2003;326:1167-70.  Back to cited text no. 3
Sismondo S. Pharmaceutical company funding and its consequences: A qualitative systematic review. Contemp Clin Trials 2008;29:109-13.  Back to cited text no. 4
Aranha AC, Eduardo Cde P. Effects of Er: YAG and Er, Cr: YSGG lasers on dentine hypersensitivity. Short-term clinical evaluation. Lasers Med Sci 2012;27:813-8.  Back to cited text no. 5
Biagi R, Cossellu G, Sarcina M, Pizzamiglio IT, Farronato G. Laser-assisted treatment of dentinal hypersensitivity: A literature review. Ann Stomatol (Roma) 2015;6:75-80.  Back to cited text no. 6
Bhavikatti SK, Bhardwaj S, Prabhuji ML. Current applications of nanotechnology in dentistry: A review. Gen Dent 2014;62:72-7.  Back to cited text no. 7
Yin Y, Yun S, Fang J, Chen H. Chemical regeneration of human tooth enamel under near-physiological conditions. Chemical Communications 2009:5892-4.  Back to cited text no. 8


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