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| LETTER TO EDITOR |
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| Year : 2016 | Volume
: 6
| Issue : 1 | Page : 44 |
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Author's Reply
Vasudev Ballal1, Jothi Varghese2
1 Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, India
2 Department of Periodontics, Manipal College of Dental Sciences, Manipal University, Manipal, Karnataka, India
| Date of Web Publication | 16-Dec-2015 |
Correspondence Address:
Vasudev Ballal
Department of Conservative Dentistry and Endodontics, Manipal College of Dental Sciences, Manipal University, Manipal - 576 104, Karnataka
India
 Source of Support: None, Conflict of Interest: None  | Check |
How to cite this article:
Ballal V, Varghese J. Author's Reply. Saudi Endod J 2016;6:44 |
Dear Drs. Sinha and Vasudeva, thank you very much for responding to our letter on your published article in Saudi Endodontic Journal 2015;5(3);182-186. I do agree with your thought of using agar diffusion test for conducting the pilot study for evaluating the antimicrobial efficacy of the test irrigants, which you have used in your study. However, due to the various drawbacks of agar diffusion test as I had mentioned in my letter earlier, there are always chances of having a false negative results. Hence, instead of using agar diffusion test, a time kill assay or direct contact method can be used since, it enables in understanding the dynamics and kinetics of medicament action on microbial viability at the appropriate concentration to be chosen for the clinically simulating models.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
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