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LETTER TO EDITOR
Year : 2019  |  Volume : 9  |  Issue : 2  |  Page : 148

Chitosan-silver nanocomposite as an endodontic irrigant


1 Sanitation 1 Medical Academic Center, Bangkok, Thailand
2 Department of Community Medicine, Dr. D.Y. Patil University, Navi Mumbai, Maharashtra, India

Date of Web Publication3-Apr-2019

Correspondence Address:
Dr. Beuy Joob
Sanitation 1 Medical Academic Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/sej.sej_50_17

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How to cite this article:
Joob B, Wiwanitkit V. Chitosan-silver nanocomposite as an endodontic irrigant. Saudi Endod J 2019;9:148

How to cite this URL:
Joob B, Wiwanitkit V. Chitosan-silver nanocomposite as an endodontic irrigant. Saudi Endod J [serial online] 2019 [cited 2019 Apr 21];9:148. Available from: http://www.saudiendodj.com/text.asp?2019/9/2/148/255364

Sir,

The report published by Saudi Endodontic Journal (issue #2, 2017) on “Chitosan-silver nanocomposite as an endodontic irrigant” is very interesting.[1] Babu et al. mentioned that “chitosan-silver nanocomposite as an endodontic irrigant can inhibit the growth of Candida albicans in combination with standard irrigation protocol.”[1] It is no doubt that the use of silver nanoparticle-based agent can be helpful and has a side activity against microbe. However, there are also concerns on the possible unwanted toxicity of using silver nanoparticle. It should be noted that if the silver nanoparticle is exactly used in vivo in human, the absorption cannot be avoided and there are many possible toxicities of silver nanoparticle. The well-known possible effects are on the reproductive and hematological system.[2],[3] Hence, before Babu et al. concluded that “chitosan-silver nanocomposite can be an alternative option provided all the ideal properties of an irrigant are satisfied,”[1] there should be a concern on possible forgotten, unwanted effect of the nanocomposite.

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Nil.

Conflicts of interest

There are no conflicts of interest.

 
  References Top

1.
Babu B, Nair RS, Angelo JM, Mathai V, Vineet RV. Evaluation of efficacy of chitosan-silver nanocomposite on Candida albicans when compared to three different antifungal agents in combination with standard irrigation protocol: An ex vivo study. Saudi Endod J 2017;7:87-91.  Back to cited text no. 1
  [Full text]  
2.
Wiwanitkit V, Sereemaspun A, Rojanathanes R. Effect of gold nanoparticles on spermatozoa: The first world report. Fertil Steril 2009;91:e7-8.  Back to cited text no. 2
    
3.
Wiwanitkit V, Sereemaspun A, Rojanathanes R. Effect of gold nanoparticle on the microscopic morphology of white blood cell. Cytopathology 2009;20:109-10.  Back to cited text no. 3
    




 

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