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LETTER TO EDITOR
Year : 2016  |  Volume : 6  |  Issue : 1  |  Page : 43-44

Author's Reply


Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh, India

Date of Web Publication16-Dec-2015

Correspondence Address:
Agrima Vasudeva
Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh - 244 001
India
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Source of Support: None, Conflict of Interest: None


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How to cite this article:
Vasudeva A, Sinha DJ. Author's Reply. Saudi Endod J 2016;6:43-4

How to cite this URL:
Vasudeva A, Sinha DJ. Author's Reply. Saudi Endod J [serial online] 2016 [cited 2019 Sep 19];6:43-4. Available from: http://www.saudiendodj.com/text.asp?2016/6/1/43/172003



Respected sir,

First of all, we would like to thank you for taking your precious time out for reading and sending suggestions regarding our study. Sir, this was a preliminary study just to find out which of the herbal irrigants used have a good antibacterial action against Enterococcus faecalis. As until date, no study has compared all these irrigants together, so we thought of a short study just to find out whether these herbal irrigants were as efficacious as their chemical counterparts already well-established in the market. We had thought of clinically simulating studies and studies involving dentinal tubule disinfection models with microbial biofilms to be conducted only if our results came out to be good. As you already know these kinds of studies do involve a lot of hard work, thereby taking a lot of time and materials. Hence, if the results are not good with agar diffusion method, one could change the test groups accordingly for future studies involving more work. By conducting this study, we came to know that Curmuma longa has a greater potential than Melaleuca alternifolia. In addition, for future studies we wanted to take less groups so we wanted to eliminate the groups that at this stage had less or did not exhibit antibacterial potential. We have conducted researches involving dentinal disinfection and biofilms models [1],[2],[3],[4] and, of course, agree with you that these studies take into account lot of other factors while simulating clinical scenario. However, to have an idea of the test groups, restrict unnecessary groups, save on the expenses and time; we intentionally conducted this research involving agar disc diffusion. Now we know that group like ethanol need not be taken in future studies; and M. alternifolia can also be excluded; so a further research involving dentinal tubule disinfection model with E. faecalis biofilm should be carried out having sodium hypochlorite, chlorhexidine, and C. longa (Turmeric) as test irrigants and saline as negative control. We have conducted a similar study taking into account these facts which is under progress for publication. Sir, your suggestions are well taken and we are already in the process on working upon them.

 
  References Top

1.
Garg P, Tyagi SP, Sinha DJ, Singh UP, Malik V, Maccune ER. Comparison of antimicrobial efficacy of propolis, Morinda citrifolia, Azadirachta indica, triphala, green tea polyphenols and 5.25% sodium hypochlorite against Enterococcus fecalis biofilm. Saudi Endod J 2014;4:122-7.  Back to cited text no. 1
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2.
Tyagi SP, Sinha DJ, Garg P, Singh UP, Mishra CC, Nagpal R. Comparison of antimicrobial efficacy of propolis, Morinda citrifolia, Azadirachta indica (Neem) and 5% sodium hypochlorite on Candida albicans biofilm formed on tooth substrate: An in-vitro study. J Conserv Dent 2013;16:532-5.  Back to cited text no. 2
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3.
Vaghela DJ, Kandaswamy D, Venkateshbabu N, Jamini N, Ganesh A. Disinfection of dentinal tubules with two different formulations of calcium hydroxide as compared to 2% chlorhexidine: As intracanal medicaments against Enterococcus faecalis and Candida albicans: An in vitro study. J Conserv Dent 2011;14:182-6.  Back to cited text no. 3
[PUBMED]  Medknow Journal  
4.
Sinha DJ, Vasudeva A, Gowhar O, Garg P, Sinha A, Prakash P. Comparison of antimicrobial efficacy of propolis, Azadirachta indica (Neem), Melaleuca alternifolia (Tea tree oil), Curcuma longa (Turmeric) and 5% sodium hypochlorite on Candida albicans biofilm formed on tooth substrate: An in-vitro study. J Pharm Biomed Sci 2015;5:469-74.  Back to cited text no. 4
    




 

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